We study how cells adapt at the molecular level, focusing on the process of translation of cellular genetic information into protein molecules. Our analyses extend from the near-instantaneous cellular responses to environmental stress to the multi-million-year evolutionary divergence of species.

Our research concentrates on massive assembly of proteins and RNA in response to changes in the cellular environment. We exploit our biological discoveries by engineering self-assembling molecules to do useful work.

Congratulations to Hendrik for being awarded an NIH NRSA F30 via the National Institute of Environmental Health Sciences for his project, “Understanding mRNA condensation and its role in translational control during stress”!

Posted 22 Jan 2021 by Sammy

Congratulations to Kyle for winning the Grier Prize (for Innovative Research in the Biophysical Sciences) for his project, “How immune cells transduce fever.” The purpose of the prize is to support UChicago Biophysics students who seek to develop new areas of research that may involve high risk or require development of new technology.

Posted 18 Dec 2020 by Sammy

Congratulations to undergraduate Rosalind Pan for winning the Liew Fellowship! Her project is titled “Alignment-free evolutionary analysis of unalignable protein sequences.”

Posted 11 Dec 2020 by Sammy

Sammy was awarded an NIH NRSA F31 via the National Institute of Environmental Health Sciences for her project “Cellular stress sensing via biomolecular condensation”! Congratulations to Sammy!

Posted 17 Aug 2020 by Sammy
Published 18 Aug 2020
Published 07 Aug 2020
Published 15 Mar 2019
A Nobel Prize for evolution
Drummond and Bloom Evolution 2019
Published 01 Mar 2019