We study how cells adapt at the molecular level, focusing on the process of translation of cellular genetic information into protein molecules. Our analyses extend from the near-instantaneous cellular responses to environmental stress to the multi-million-year evolutionary divergence of species.

Our research concentrates on massive assembly of proteins and RNA in response to changes in the cellular environment. We exploit our biological discoveries by engineering self-assembling molecules to do useful work.

With Laura Lackner’s group’ at Northwestern, we’ve just been awarded two years of collaborative funding to study how older cells retain stress-triggered aggregates by tethering aggregates to organelles. Thanks to the Chicago Biomedical Consortium, and the Searle Funds at The Chicago Community Trust, for this Catalyst award!

Posted 28 Apr 2016 by Allan

Scientific American produced a video of Allan discussing a merger of cell biology and art: 3D printing a budding yeast cell with heat-shock granules.

Posted 25 Jan 2016 by Allan

She’s official! Cat passed her prelim in the Biophysics program.

Posted 08 Dec 2015 by Allan

The Scientist features our study as an Editor’s Choice in Molecular and Cell Biology.

Posted 03 Dec 2015 by Allan
Posted 19 Dec 2015 by Allan
Posted 10 Sep 2015 by Allan
Posted 28 May 2015 by Allan
Posted 22 Apr 2015 by Allan